A team of botanists and Ayurveda experts at our R&D center review these scholarly texts and shortlist suitable herbs for further research. The availability and sustainability of these herbs are first ensured before research is initiated.
Analysing the Herbs
Himalaya's phytochemistry team studies the geographical and seasonal variations of the marker profiles of these herbs. Active markers within these herbs, which are responsible for its therapeutic property, may vary depending on whether they are cultivated or sourced from the wild. Phytochemical profiling is established from different seasons and geographical locations to ensure batch-to-batch consistency, good quality and standardization.
The quality of herbs is maintained either by cultivating herbs under supervision of agricultural scientists or by practicing sustainable collection and harvesting practices under the supervision of trained botanists. Herbs have to further pass through stringent quality checks as per internal specifications laid out by our scientists.
Herbal Research to New Levels
With a focus on taking herbal research to new levels, Himalaya's scientists have adopted bioassay guided fractionation and purification technology to identify the active fractions. This ensures that the herbal preparation is standardized and formulation has required levels of bioactive compounds to elicit the pharmacological response. This technology will continue to help in identifying phytoactive principles responsible for efficacy, synergy and bioavailability.
Himalaya’s scientists are leveraging this technology for innovative treatments of ailments including cancer, diabetes and depression as well as for specialized products in skin, oral and hair care categories.
Super Critical Fluid (SCF) extraction is one of the fast growing technologies for extracting herbal materials without using chemical solvents. Himalaya’s scientists are leveraging this technology during research and development for the extraction of beneficial bioactive compounds. This ensures no solvent residues in herbal preparation while delivering to the safety and efficacy of the products.
Extracts from single herb or a combination of herbs are initially tested on disease models of cell lines to evaluate the efficacy of the drug. Once efficacy is confirmed, these extracts undergo rigorous toxicity tests and mutagen studies to ensure that it is safe to test on humans. The extracts are formulated into the desired dosage forms (capsules, tablets, caplets, syrups and drops) and then enter human clinical trials. All clinical trials follow Indian and international norms on human subject testing.
The Process of Testing Drugs
The numbers of patients increase in each phase
PHASE 2 & 3